16 Panel Clicker Multi-Drug Urine Test Cup- (BX) 25 Cups (FUO)

The 16 Panel Clicker Multi-Drug Urine Test is intended for screening for the presence of drugs and their metabolites in urine at specific cut-off concentrations

16 Panel Clicker tests for: AMP1000, BAR300, BUP10, BZO300, COC300, ETG500, FEN300, K2(50), MDMA500, MET1000, MTD300, OPI2000, OXY100, PCP25, THC50, TRA200

Forensic Use Only (FUO)

• Multi-Drug Urine Test Cup
  
• Number of Panels: 16
  
• Forensic Use Only (FUO)
  
• Up to 99% Accuracy
  
• Up to 24-Month Shelf Life
  
• Adulterants: No
  
• Reading Type: Visual
  
• Application: IVD Device
  
• Packaged 25 Tests/Box
  
• Features / Benefits
  

Feature & Benefits

• Lateral flow chromatographic immunoassay for the qualitative detection of multiple drugs and drug metabolites in urine at specific cut-off concentrations
  
• All-in-one urine based test that can be utilized in practically any drug screening scenario
  
• Simple non-invasive procedure
  
• Fast, easy to interpret results in 5 minutes
  
• Tests for: Amphetamine (AMP), Barbiturates (BAR), Buprenorphine (BUP), Benzodiazepines (BZO), Cocaine (COC), Ethyl Glucuronide (ETG), Fentanyl (FEN), Methylenedioxymethamphetamine (MDMA), Methamphetamine (MET), Methadone (MTD), Opiates (OPI), Oxycodone (OXY), Phencyclidine (PCP), Marijuana (THC), Tramadol (TRA)

This test will detect other related compounds, please refer to the Analytical Specificity table in this package insert.

AMP: Amphetamine is a sympathomimetic amine with therapeutic indications. The drug is often self-administered by nasal inhalation or oral ingestion.1

BAR: Barbiturates are central nervous system depressants. They are used therapeutically as sedatives, hypnotics, and anticonvulsants. Barbiturates are almost always taken orally as capsules or tablets. The effects resemble those of intoxication with alcohol. Chronic use of barbiturates leads to tolerance and physical dependence. Short acting Barbiturates taken at 400 mg/day for 2-3 months can produce a clinically significant degree of physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death.

BZO: Benzodiazepines are central nervous system (CNS) depressants commonly prescribed for the short-term treatment of anxiety and insomnia. In general, benzodiazepines act as hypnotics in high doses, as anxiolytics in moderate doses and as sedatives in low doses. The use of benzodiazepines can result in drowsiness and confusion. Psychological and physical dependence on benzodiazepines can develop if high doses of the drug are given over a prolonged period. Benzodiazepines are taken orally or by intramuscular or intravenous injection, and are extensively oxidized in the liver to metabolites. Benzodiazepines can be detected in oral fluid after use.

BUP: Buprenorphine is a semisynthetic opioid analgesic derived from thebain, a component of opium. It has a longer duration of action than morphine when indicated for the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence. Low doses buprenorphine produces sufficient agonist effect to enable opioid-addicted individuals to discontinue the misuse of opioids without experiencing withdrawal symptoms. Buprenorphine carries a lower risk of abuse, addiction, and side effects compared to full opioid agonists because of the “ceiling effect”, which means no longer continue to increase with further increases in dose when reaching a plateau at moderate doses. However, it has also been shown that Buprenorphine has abuse potential and may itself cause dependency. Buprenorphine was rescheduled from Schedule V to Schedule III drug just before FDA approval of Suboxone and Subutex.

COC: Cocaine is a potent central nervous system (CNS) stimulant and a local anesthetic derived from the coca plant (erythroxylum coca).1

COT: Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking ssociety is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays.

MDMA: MDMA is an abbreviation for the chemical methylenedioxymethamphetamine MDMA. It has street many name including Ecstasy, X, XTC, E, Love Doves, Clarity, Adam, Disco Biscuits and Shamrocks, etc. it is a stimulant with hallucinogenic tendencies, described as an empathogen as it releases mood-altering chemicals, such as cartooning and L-dopa, in the brain and may generate feelings of love and friendliness. MDMA is a Class A drug, in the same category as heroin and cocaine. The adverse effects of MDMA use include elevated blood pressure, hyperthermia, anxiety, paranoia, and insomnia. Overdoses of MDMA can be fatal, often resulting in heart failure or heart stoke. MDMA belongs to a family of man-made drugs; its relatives include MDA (methylenedioxy MDMA), the parent drug of MDMA, and MDEA (methylenedioxyethyl MDMA), also known as EVE. They all share the MDMA-like effects. MDMA is administered either by oral ingestion or intravenous injection. MDMA tablets come in different sizes and colors, and often have logos such as doves on them. Its clinical dose is 50-100 mg; the threshold toxic dose is 500mg. The effects of MDMA begin 30 minutes after intake. They peak in an hour and last for 2-3 hours. it is detectible in the saliva for up to 3 days after use.

FEN: Fentanyl, belongs to powerful narcotics analgesics, and is a special opiates receptor stimulant. Fentanyl is one of the varieties that been listed in management of United Nations “Single Convention of narcotic drug in 1961”. Among the opiates agents that under international control, fentanyl is one of the most commonly used to cure moderate to severe pain1. After continuous injection of fentanyl, the sufferer will have the performance of protracted opioid abstinence syndrome, such as ataxia and irritability etc2,3, which presents the addiction after taking fentanyl in a long time. Compared with drug addicts of amphetamine, drug addicts who take fentanyl mainly have got the possibility of higher infection rate of HIV, more dangerous injection behavior and more lifelong medication overdose.

KET: Ketamine is a dissociative anesthetic developed in 1963 to replace PCP (Phencyclidine). While Ketamine is still used in human anesthesia and veterinary medicine, it is becoming increasingly abused as a street drug.>Ketamine is molecularly similar to PCP and thus creates similar effects including numbness, loss of coordination, sense of invulnerability, muscle rigidity, aggressive / violent behavior, slurred or blocked speech, exaggerated sense of strength, and a blank stare. There is depression of respiratory function but not of the central nervous system, and cardiovascular function is maintained.

LSD: D-lysergic acid diethylamide (LSD) is the most potent hallucinogenic substance known to man. Dosages of LSD are measured in micrograms, or millionths of a gram. By comparison, dosages of cocaine and heroin are measured in milligrams, or thousandths of a gram. Compared to other hallucinogenic substances, LSD is 100 times more potent than psilocybin and psilocin and 4,000 times more potent than mescaline. The dosage level that will produce a hallucinogenic effect in humans generally is considered to be 25 micrograms.

THC: Tetrahydrocannabinol, the active ingredient in the marijuana plant (cannabis sativa), is detectable in oral fluid shortly after use. The detection of the drug is thought to be primarily due to the direct exposure of the drug to the mouth (oral and smoking administrations) and the subsequent sequestering of the drug in the buccal cavity.2

EDDP: Methadone (MTD) is a synthetic analgesic drug that is originally used in the treatment of narcotic addicts. Among the psychological effects induced by using methadone are analgesia, sedation and respiratory depression. Overdose of methadone may cause coma or even death. It is administered orally or intravenously and is metabolized in the liver. The kidneys are a major route of methadone excretion. Methadone has a biological half-life of 16-50 hours. EDDP (2-Ethyliden-1,5-Dimethyl- 3,3-Diphenylpyrrolidine) is the most important metabolite of methadone. It is formed by N-demethylation and cyclization of methadone in the liver. The detection of the metabolite EDDP instead of methadone itself is useful, because interferences of the patient’s metabolism are avoided.

MTD: Methadone is a synthetic analgesic drug originally used for the treatment of narcotic addiction. In addition to use as a narcotic agonist, methadone is being used more frequently as a pain management agent. The psychological effects induced by using methadone are analgesia, sedation, and respiratory depression. Based on the saliva/plasma ratio calculated over salivary pH ranges of 6.4-7.6 for therapeutic or recreational doses of methadone, a cut-off <50 ng/mL is suggested. Due to this recommendation, the cut-off level of the methadone test was calibrated to 30 ng/mL.

MET: Methamphetamine is a potent stimulant chemically related to amphetamine but with greater CNS stimulation properties. The drug is often self-administered by nasal inhalation, smoking or oral ingestion.1

MQL: Methaqualone is a quinazoline derivative that was first synthesized in 1951 and found clinically effective as a sedative and hypnotic in 1956.It soon gained popularity as a drug of abuse and in 1984 was removed from the US market due to extensive misuse. It is occasionally encountered in illicit form, and is also available in Europe on countries in combination with diphenhydramine (Mandrax). Methaqualone is extensively metabolized in vivo principally by hydroxylation at every possible position on the molecule.

MDPV: “Bath salts”, a form of designer drugs, also promoted as ‘plant food’ or ‘research chemicals’ and is sold mainly in head shops, on the Internet, and at other retail locations. Designer drugs were developed in recent years to subvert law enforcement and drug testing agencies and are advertised a ‘legal’ high. The technical term for ‘bath salts’ is substituted cathinone. Substituted cathinone is synthetic, concentrated version of the stimulant chemical in Khat. Khat is a plant that is cultivated and used in East Africa and the Middle East. It has a stimulant effect on the user and can be quite dangerous. The white crystals resemble legal bathing salts, thus the name of ‘bath salts’.Established as one of the main ingredients for ‘bath salts’ among other synthetic stimulants like Mephedrone, Methylone, Butylone and Methedrone, MDPV started appearing around 2004 when it was popularized as a club drug, often used in combination with alcohol, GHB, cannabis and other drugs of abuse, for its desired effects such as euphoria, alertness, talkativeness, and sexual arousal. There are currently no prescribed uses for the synthetic stimulants.

6-MAM:6-Monoacetylmorphine (6-MAM) or 6-acetylmorphine is one of three active metabolites of heroin (diacetylmorphine), the others being morphine and the much less active 3-monoacetylmorphine (3-MAM). 6-MAM is rapidly created from heroin in the body, and then is either metabolized into morphine or excrete. Since 6-MAM is a unique metabolite to heroin, its presence in the saliva confirms that heroin was the opioid used. This is significant because on a saliva immunoassay drug screen, the test typically tests for morphine, which is a metabolite of a number of legal and illegal opiates/opioids such as codeine, morphine sulfate, and heroin.